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ARA-290

$69.99

ARA-290 (Cibinetide) – Research Peptide
Class: Erythropoietin (EPO) derivative / Innate Repair Receptor (IRR) ligand
Form: Lyophilized powder
Purity: ≥ 99% (HPLC verified)
Storage (dry): Room temperature, away from light
Storage (reconstituted): Refrigerate 2–8°C
Solvent compatibility: Bacteriostatic Water (preferred)
ARA-290 is a synthetic 11-amino acid peptide derived from the B-helix of erythropoietin. Unlike standard EPO, ARA-290 does not stimulate red blood cell production; instead, it selectively targets the Innate Repair Receptor (IRR). In research settings, it is a primary subject for investigating the mitigation of tissue damage and the activation of endogenous repair mechanisms following metabolic or inflammatory stress.
Key Research Focus Areas
Neuropathic Signaling: Investigation of the peptide’s role in modulating small fiber neuropathy and peripheral nerve sensitivity models.
Innate Repair Receptor (IRR) Activation: Study of the signaling pathways involved in tissue protection and the downregulation of pro-inflammatory cytokines.
Glycemic Control & Metabolic Stress: Analysis of its impact on islet cell survival and insulin sensitivity in metabolic research models.
Macrophage Polarization: Researching the shift from pro-inflammatory (M1) to anti-inflammatory/repair (M2) macrophage phenotypes.
Cytoprotection in Chronic Stress: Evaluation of the peptide’s ability to prevent apoptosis in cells subjected to hypoxia or high-glucose environments.
Format Options
10 mg lyophilized powder
Optional BAC solvent available separately
Important Notice
All products are sold for laboratory research use only. Not for human consumption, injection, or diagnostic use.

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ARA-290

Research Peptide

ARA-290 is a synthetic peptide derived from erythropoietin that has gained attention in preclinical research for its potential role in tissue protection, inflammation modulation, and nerve regeneration. It is widely investigated for its activity on innate repair pathways without stimulating red blood cell production.

Potential Research Applications

Current preclinical and investigational research has explored ARA-290 for its potential role in:

  • Supporting nerve regeneration
  • Promoting tissue repair
  • Modulating inflammatory responses
  • Supporting recovery following nerve injury
  • Protecting cellular integrity
  • Supporting connective tissue health
  • Investigating regenerative signaling pathways
  • Reducing inflammation in experimental models

Mechanism of Action

Although research is ongoing, ARA-290 has demonstrated activity through several biological pathways, including:

  • Activation of innate tissue repair receptors
  • Modulation of inflammatory signaling pathways
  • Support of cellular regeneration and repair
  • Protection of nerve and endothelial tissue
  • Promotion of tissue recovery in experimental models

These mechanisms have made ARA-290 a significant area of interest in regenerative medicine research.

Product Information

  • High-purity lyophilized research peptide
  • Manufactured under strict quality standards
  • Third-party tested for identity and purity
  • Intended exclusively for laboratory and scientific research applications

Research Disclaimer

This product is intended for laboratory research purposes only. It is not approved by the U.S. Food and Drug Administration (FDA) for human or veterinary use and is not intended to diagnose, treat, cure, or prevent any disease. It should only be handled by qualified professionals in appropriate research settings.

weight

10mg

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