{"product_id":"ara-290","title":"ARA-290 (Cibinetide) – Research Peptide","description":"\u003cp\u003eARA-290 (Cibinetide) – Research Peptide\u003cbr\u003eClass: Erythropoietin (EPO) derivative \/ Innate Repair Receptor (IRR) ligand  \u003cbr\u003eForm: Lyophilized powder\u003cbr\u003ePurity: ≥ 99% (HPLC verified)\u003cbr\u003eStorage (dry): Room temperature, away from light\u003cbr\u003eStorage (reconstituted): Refrigerate 2–8°C\u003cbr\u003eSolvent compatibility: Bacteriostatic Water (preferred)  \u003cbr\u003eARA-290 is a synthetic 11-amino acid peptide derived from the B-helix of erythropoietin. Unlike standard EPO, ARA-290 does not stimulate red blood cell production; instead, it selectively targets the Innate Repair Receptor (IRR). In research settings, it is a primary subject for investigating the mitigation of tissue damage and the activation of endogenous repair mechanisms following metabolic or inflammatory stress.  \u003cbr\u003eKey Research Focus Areas\u003cbr\u003eNeuropathic Signaling: Investigation of the peptide's role in modulating small fiber neuropathy and peripheral nerve sensitivity models.\u003cbr\u003eInnate Repair Receptor (IRR) Activation: Study of the signaling pathways involved in tissue protection and the downregulation of pro-inflammatory cytokines.\u003cbr\u003eGlycemic Control \u0026amp; Metabolic Stress: Analysis of its impact on islet cell survival and insulin sensitivity in metabolic research models.\u003cbr\u003eMacrophage Polarization: Researching the shift from pro-inflammatory (M1) to anti-inflammatory\/repair (M2) macrophage phenotypes.  \u003cbr\u003eCytoprotection in Chronic Stress: Evaluation of the peptide’s ability to prevent apoptosis in cells subjected to hypoxia or high-glucose environments.  \u003cbr\u003eFormat Options\u003cbr\u003e10 mg lyophilized powder    \u003cbr\u003eOptional BAC solvent available separately\u003cbr\u003eImportant Notice\u003cbr\u003eAll products are sold for laboratory research use only. Not for human consumption, injection, or diagnostic use.\u003c\/p\u003e","brand":"My Store","offers":[{"title":"Default Title","offer_id":44166663929942,"sku":"10mg","price":74.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0682\/3565\/7302\/files\/5_-_Amino-_1MQ.png?v=1777082800","url":"https:\/\/regencypeptides.com\/products\/ara-290","provider":"My Store","version":"1.0","type":"link"}