5-Amino-1MQ

5-Amino-1MQ – Research Compound
Class: Small molecule / NNMT inhibitor
Form: Lyophilized powder or Crystalline powder
Purity: ≥ 99% (HPLC verified)
Storage (dry): Room temperature, away from light
Storage (reconstituted): Refrigerate 2–8°C
Solvent compatibility: DMSO (preferred) or Bacteriostatic Water (concentration dependent)
5-Amino-1MQ is a cell-permeable, selective inhibitor of the enzyme nicotinamide N-methyltransferase (NNMT). In laboratory research, it is primarily utilized to study the regulation of metabolic pathways, NAD+ metabolism, and the role of NNMT in adipocytes and muscle cells.
Key Research Focus Areas
Metabolic Rate Regulation: Investigation of intracellular NAD+ levels and their influence on energy expenditure in adipose tissue models.
Skeletal Muscle Homeostasis: Research into the compound’s impact on muscle fiber regeneration and protein synthesis signaling.
NNMT Pathway Inhibition: Study of the selective blocking of NNMT to analyze downstream effects on DNA methylation and gene expression.
Obesity & Diabetes Models: Evaluation of the compound’s role in lipid metabolism and insulin sensitivity markers in pre-clinical settings.
Cellular Senescence: Analysis of its potential to influence age-related cellular decline and mitochondrial efficiency.
Format Options
5 mg or 50 mg lyophilized powder
Optional DMSO or BAC solvent available separately
Important Notice
All products are sold for laboratory research use only. Not for human consumption, injection, or diagnostic use