MOTS-c

MOTS-c – Research Peptide

Class: Mitochondrial-derived peptide
Form: Lyophilized powder (White)
Purity: ≥ 99% (HPLC verified)
Storage (dry): Room temperature (Short-term) / -20°C (Long-term), away from light
Storage (reconstituted): Refrigerate at 2–8°C (Use within 24–48 hours for maximum stability)
Solvent compatibility: Bacteriostatic Water or Sterile Water

MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a naturally occurring mitochondrial-derived peptide consisting of 16 amino acids. In research environments, MOTS-c is primarily studied for its involvement in cellular metabolism, mitochondrial signaling, glucose utilization, and cellular responses to metabolic stress.

Key Research Focus Areas

Metabolic Regulation & Glucose Utilization: Investigation of MOTS-c’s role in cellular glucose metabolism and pathways associated with metabolic homeostasis.

AMPK Signaling: Research into the interaction between MOTS-c and AMP-activated protein kinase (AMPK), a key cellular energy-sensing pathway.

Mitochondrial Function: Evaluation of MOTS-c in laboratory models investigating mitochondrial signaling, energy metabolism, and cellular stress responses.

Oxidative Stress & Cellular Protection: Study of its potential involvement in cellular responses to oxidative and metabolic stress.

Exercise & Metabolic Adaptation: Investigation of MOTS-c signaling in experimental models related to exercise, energy expenditure, and metabolic adaptation.

Cellular Stress Response: Research into how MOTS-c may interact with cellular pathways involved in maintaining metabolic balance during periods of stress.