ARA-290 (Cibinetide) – Research Peptide

ARA-290 (Cibinetide) – Research Peptide
Class: Erythropoietin (EPO) derivative / Innate Repair Receptor (IRR) ligand  
Form: Lyophilized powder
Purity: ≥ 99% (HPLC verified)
Storage (dry): Room temperature, away from light
Storage (reconstituted): Refrigerate 2–8°C
Solvent compatibility: Bacteriostatic Water (preferred)  
ARA-290 is a synthetic 11-amino acid peptide derived from the B-helix of erythropoietin. Unlike standard EPO, ARA-290 does not stimulate red blood cell production; instead, it selectively targets the Innate Repair Receptor (IRR). In research settings, it is a primary subject for investigating the mitigation of tissue damage and the activation of endogenous repair mechanisms following metabolic or inflammatory stress.  
Key Research Focus Areas
Neuropathic Signaling: Investigation of the peptide's role in modulating small fiber neuropathy and peripheral nerve sensitivity models.
Innate Repair Receptor (IRR) Activation: Study of the signaling pathways involved in tissue protection and the downregulation of pro-inflammatory cytokines.
Glycemic Control & Metabolic Stress: Analysis of its impact on islet cell survival and insulin sensitivity in metabolic research models.
Macrophage Polarization: Researching the shift from pro-inflammatory (M1) to anti-inflammatory/repair (M2) macrophage phenotypes.  
Cytoprotection in Chronic Stress: Evaluation of the peptide’s ability to prevent apoptosis in cells subjected to hypoxia or high-glucose environments.  
Format Options
10 mg lyophilized powder    
Optional BAC solvent available separately
Important Notice
All products are sold for laboratory research use only. Not for human consumption, injection, or diagnostic use.